于永乐

    2019-10-10 10:01:31           浏览数:0

  基本信息

  姓名:       于永乐           性别:男

  政治面貌:******党员       学位:理学博士

  职称:讲师

  社会兼职情况:中国畜牧兽医学会动物生理生化分会会员 山东省科技特派员

  获奖情况: 娱乐天地平台优秀共产党员,山东省优秀毕业生

  教育背景

  2007-09至2011-07:娱乐天地平台,动物科学专业,学士

  2011-09至2014-07:娱乐天地平台,预防兽医学专业,硕士

  2015-09至2019-07:中国农业大学,生物化学与分子生物学专业,博士

  研究方向

  宠物及毛皮动物细小病毒感染性克隆的构建及防控技术研究

  新型诊断试剂和疫苗的研发

  擅长病毒反向遗传研究技术,临床抗原抗体检测,原代细胞及传代细胞培养,病毒分离鉴定,免疫学相关实验,病理切片技术以及实验犬攻毒实验等

  主持、参与课题情况

  参与纵向项目-课题名称:宠物病毒性传染病诊断和鉴别诊断技术研究与应用

  项目来源:十三五国家重点研发计划

  经费:90万

  参与横向项目-水貂犬瘟热、病毒性肠炎二联灭活疫苗的研制  150万犬瘟热、犬细小病毒病二联灭活疫苗的研制   150万

  发表论文

  1. Yu Y., Su J., Wang J., Xi J., Mao Y., Hou Q., Zhang X., Liu W. (2017). A rapid method for establishment of a reverse genetics system for canine parvovirus. Virus Genes 53, 876-882.

  2. Yu Y., Zhang J., Wang J., Xi J., Zhang X., Li P., Liu Y., Liu W. (2018). Naturally-occurring right terminal hairpin mutations in three genotypes of canine parvovirus (CPV-2a, CPV-2b and CPV-2c) have no effect on their growth characteristics. Virus Research 261,31-36.

  3. Zhang C, Yu Y, Yang H, Li G, Yu Z, Zhang H, Shan H. (2014). Development of a PCR-RFLP assay for the detection and differentiation of canine parvovirus and mink enteritis virus. J Virol Methods 210:1-6.

  4. Xi J., Wang J., Yu Y., Zhang X., Mao Y., Hou Q., Liu W. (2016). Genetic characterization of the complete genome of an Aleutian mink disease virus isolated in north China. Virus Genes 52, 463-473.

  5. Xi J., Zhang Y., Wang J., Yu Y., Zhang X., Li Z., Cui S., Liu W. (2017). Generation of an infectious clone of AMDV and identification of capsid residues essential for infectivity in cell culture. Virus Research 242, 58-65.

  6. Zhang, X., Wang, J., Mao, Y., Xi, J., Yu, Y., and Liu, W. (2017). Induction and suppression of type I interferon responses by mink enteritis virus in CRFK cells. Veterinary Microbiology 199, 8-14.

  7. Mao Y., Wang J., Hou Q., Xi J., Zhang X., Bian D., Yu Y., Wang X., Liu W. (2016). Comparison of biological and genomic characteristics between a newly isolated mink enteritis parvovirus MEV-LHV and an attenuated strain MEV-L. Virus Genes 52, 388-396.

  8. Cheng N., Zhao Y ., Han Q ., Zhang W ., Xi J ., Yu Y ., Wang H ., Li G ., Gao Y ., Yang S ., Liu W ., Xia X. (2018).Development of a reverse genetics system for a feline panleukopenia virus. Virus genes. Epub ahead of print.

  9. 于永乐,王吉贵,郗冀,毛亚萍,侯蔷,张晓梅,刘维全.犬细小病毒北京分离株的鉴定及其全基因组序列分析[J].中国兽医学报,2017,37(06):1023-1029.

  10. 于永乐,张传美,张倩,杨海燕,杨瑞梅,张洪亮,单虎.犬细小病毒山东分离株VP2基因的克隆与遗传变异分析[J].中国兽医杂志,2015,51(08):10-13.

  11. 于永乐,张传美,杨海燕,杨瑞梅,张洪亮,单虎.水貂肠炎病毒SYBR GreenⅠ荧光定量PCR检测方法的建立[J].兽类学报,2015,35(01):102-109.

  12. 于永乐,宫文妮,杨海燕,赵秀美,张传美,张洪亮,单虎.犬细小病毒山东流行株分离鉴定及其全基因组测序分析[J].中国兽医杂志,2014,50(08):6-9.

  13. 程楠,赵永坤,于永乐,希冀,王化磊,冯娜,张渭蛟,高玉伟,杨松涛,刘维全,夏咸柱.猫细小病毒HH-1/86株理化性质鉴定及全基因组测序[J].中国兽医学报,2017,37(05):818-822.